Association Study between Functional Polymorphisms of MMP9 Gene Promoter and Multiple Sclerosis Susceptibility in an Iranian Population

• Main Authors: Sima SABBAGH (Author), Zakiye NADEALI (Author), Leila DEHGHANI (Author), Vahid SHAYGANNEJAD (Author), Majid REZVANI (Author), Masih SABOORI (Author), Hamid GANJI (Author), Soheil TAHANI (Author), Farzaneh DEHGHANI (Author), Saman HOSSEINZADEH (Author), Elnaz MARZBANI (Author), Peiman SHAFIEI (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Matrix metalloproteinase-9 (MMP-9) polymorphisms, C−1562 T and -90 (CA) n repeats, which influence transcriptional activity of this gene, are proposed to play a role in MS susceptibility and its development. In the present study, the possible association of MMP-9 polymorphisms in Iranian...