Expression of interferon-inducible chemokines and sleep/wake changes during early encephalitis in experimental African trypanosomiasis.

• Main Authors: Claudia Laperchia (Author), Chiara Tesoriero (Author), Paul F Seke-Etet (Author), Valentina La Verde (Author), Valeria Colavito (Author), Gigliola Grassi-Zucconi (Author), Jean Rodgers (Author), Paul Montague (Author), Peter G E Kennedy (Author), Marina Bentivoglio (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human African trypanosomiasis or sleeping sickness, caused by the parasite Trypanosoma brucei, leads to neuroinflammation and characteristic sleep/wake alterations. The relationship between the onset of these alterations and the development of neuroinflammation is of high translational relevance, bu...