SeDeM expert system with I-optimal mixture design for oral multiparticulate drug delivery: An encapsulated floating minitablets of loxoprofen Na and its in silico physiologically based pharmacokinetic modeling

• Ngā kaituhi matua: Rauf- (Author), Muhammad Harris Shoaib (Author), Farrukh Rafiq Ahmed (Author), Rabia Ismail Yousuf (Author), Fahad Siddiqui (Author), Muhammad Talha Saleem (Author), Faaiza Qazi (Author), Momina Zarish Khan (Author), Asma Irshad (Author), Lubna Bashir (Author), Shazia Naz (Author), Muhammad Farooq (Author), Zafar Alam Mahmood (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Introduction: A SeDeM expert tool-driven I-optimal mixture design has been used to develop a directly compressible multiparticulate based extended release minitablets for gastro-retentive drug delivery systems using loxoprofen sodium as a model drug.Methods: Powder blends were subjected to stress dr...