Preparation of endostatin-loaded chitosan nanoparticles and evaluation of the antitumor effect of such nanoparticles on the Lewis lung cancer model

• Main Authors: Rui-Lin Ding (Author), Fang Xie (Author), Yue Hu (Author), Shao-Zhi Fu (Author), Jing-Bo Wu (Author), Juan Fan (Author), Wen-Feng He (Author), Yu He (Author), Ling-Lin Yang (Author), Sheng Lin (Author), Qing-Lian Wen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to prepare ES-loaded chitosan nanoparticles (ES-NPs) and evaluate the antitumor effect of these particles on the Lewis lung cancer model. ES-NPs were prepared by a simple ionic cross-linking method. The characterization of the ES-NPs, including size distribution, zeta p...