Growth differentiation factor-11 downregulates steroidogenic acute regulatory protein expression through ALK5-mediated SMAD3 signaling pathway in human granulosa-lutein cells
Abstract Background Growth differentiation factor-11 (GDF-11) belongs to the transforming growth factor-β (TGF-β) superfamily. To date, the expression of GDF-11 in the ovary and its role in regulating ovarian function are completely unknown. Ovarian granulosa cell-mediated steroidogenesis plays a pi...
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Main Authors: | Qiongqiong Jia (Author), Boqun Liu (Author), Xuan Dang (Author), Yanjie Guo (Author), Xiaoyu Han (Author), Tinglin Song (Author), Jung-Chien Cheng (Author), Lanlan Fang (Author) |
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Format: | Book |
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BMC,
2022-02-01T00:00:00Z.
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