Gene expression profiling of Trypanosoma cruzi in the presence of heme points to glycosomal metabolic adaptation of epimastigotes inside the vector.

• Main Authors: Marcia C Paes (Author), Francis M S Saraiva (Author), Natália P Nogueira (Author), Carolina S D Vieira (Author), Felipe A Dias (Author), Ana Rossini (Author), Vitor Lima Coelho (Author), Attilio Pane (Author), Fei Sang (Author), Marcos Alcocer (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite, Trypanosoma cruzi, and is transmitted by triatomine insects during its blood meal. Proliferative epimastigotes forms thrive inside the insects in the presence of heme (...