Aspirin alleviates endothelial gap junction dysfunction through inhibition of NLRP3 inflammasome activation in LPS-induced vascular injury

• Main Authors: Xing Zhou (Author), Yanjiao Wu (Author), Lifeng Ye (Author), Yunting Wang (Author), Kaimin Zhang (Author), Lingjun Wang (Author), Yi Huang (Author), Lei Wang (Author), Shaoxiang Xian (Author), Yang Zhang (Author), Yang Chen (Author)
• Format: Book
• Published: Elsevier, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The loss of endothelial connective integrity and endothelial barrier dysfunction can lead to increased vascular injury, which is related to the activation of endothelial inflammasomes. There are evidences that low concentrations of aspirin can effectively prevent cardiovascular diseases. We hypothes...