Gene by Sex Interaction for Measures of Obesity in the Framingham Heart Study

• Main Authors: Ashlee M. Benjamin (Author), Sunil Suchindran (Author), Kaela Pearce (Author), Jennifer Rowell (Author), Lillian F. Lien (Author), John R. Guyton (Author), Jeanette J. McCarthy (Author)
• Format: Book
• Published: Hindawi Limited, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity is an increasingly prevalent and severe health concern with a substantial heritable component and marked sex differences. We sought to determine if the effect of genetic variants also differed by sex by performing a genome-wide association study modeling the effect of genotype-by-sex interac...