PTPRM methylation induced by FN1 promotes the development of glioblastoma by activating STAT3 signalling

• Main Authors: Jian Song (Author), Di Zhao (Author), Guozhu Sun (Author), Jiankai Yang (Author), Zhongqiang Lv (Author), Baohua Jiao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context The phosphorylation of signal transducer and activator of transcription protein 3 (STAT3) is up-regulated in glioblastoma (GBM) cells and is regulated by protein tyrosine phosphatase receptor type M (PTPRM). Fibronectin-1 (FN1) is also reported to be up-regulated in GBM. Objective We explore...