Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations

• Main Authors: Sumiko Ikari (Author), Qiang Yang (Author), Shiou-Ling Lu (Author), Yuancai Liu (Author), Feike Hao (Author), Guoqiang Tong (Author), Shiguang Lu (Author), Takeshi Noda (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tartary buckwheat is used as an ingredient in flour and tea, as well as in traditional Chinese medicine for its antioxidant effects. Here, we found that an ethanol extract of tartary buckwheat (TBE) potently induced autophagy flux in HeLa cells by suppressing mTORC1 activity, as revealed by dephosph...