Persistence of Second and Third-Line Biologics in Inflammatory Bowel Disease: A Multi-Centre Cohort Study

• Main Authors: Timothy P. Hanrahan (Author), Robbie Chan (Author), Daniel Tassone (Author), Nik S. Ding (Author), Chamara Basnayake (Author), Julien Schulberg (Author), Abhinav Vasudevan (Author), Michael Kamm (Author), Michael De Gregorio (Author), Daniel R. van Langenberg (Author), Ola Niewiadomski (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Despite proven efficacy of biologics in inflammatory bowel disease (IBD), many exhibit primary non-response or secondary loss of response and switch to subsequent biologic(s). Here, we identified early predictors of second- and/or third-line biologic persistence in IBD, in a real-world c...