Predicting Paclitaxel Disposition in Humans With Whole‐Body Physiologically‐Based Pharmacokinetic Modeling

Paclitaxel is a commonly used drug in the treatment of multiple solid tumors, including cancers of the breast, lung, and ovaries. Despite the established exposure-pharmacodynamic relationships for paclitaxel, treatment is associated with wide interindividual pharmacokinetic variability that leads to...

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Main Authors: Qiang Fu (Author), Xinxin Sun (Author), Maryam B. Lustburg (Author), Alex Sparreboom (Author), Shuiying Hu (Author)
Format: Book
Published: Wiley, 2019-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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