Predicting Paclitaxel Disposition in Humans With Whole‐Body Physiologically‐Based Pharmacokinetic Modeling
Paclitaxel is a commonly used drug in the treatment of multiple solid tumors, including cancers of the breast, lung, and ovaries. Despite the established exposure-pharmacodynamic relationships for paclitaxel, treatment is associated with wide interindividual pharmacokinetic variability that leads to...
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Main Authors: | Qiang Fu (Author), Xinxin Sun (Author), Maryam B. Lustburg (Author), Alex Sparreboom (Author), Shuiying Hu (Author) |
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Format: | Book |
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Wiley,
2019-12-01T00:00:00Z.
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