A novel neoantigen discovery approach based on chromatin high order conformation

• Main Authors: Yi Shi (Author), Mingxuan Zhang (Author), Luming Meng (Author), Xianbin Su (Author), Xueying Shang (Author), Zehua Guo (Author), Qingjiao Li (Author), Mengna Lin (Author), Xin Zou (Author), Qing Luo (Author), Yaoliang Yu (Author), Yanting Wu (Author), Lintai Da (Author), Tom Weidong Cai (Author), Guang He (Author), Ze-Guang Han (Author)
• Format: Book
• Published: BMC, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background High-throughput sequencing technology has yielded reliable and ultra-fast sequencing for DNA and RNA. For tumor cells of cancer patients, when combining the results of DNA and RNA sequencing, one can identify potential neoantigens that stimulate the immune response of the T cell....