Unraveling and Targeting Myocardial Regeneration Deficit in Diabetes

• Autori principali: Claudia Molinaro (Autore), Luca Salerno (Autore), Fabiola Marino (Autore), Mariangela Scalise (Autore), Nadia Salerno (Autore), Loredana Pagano (Autore), Antonella De Angelis (Autore), Eleonora Cianflone (Autore), Daniele Torella (Autore), Konrad Urbanek (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Cardiomyopathy is a common complication in diabetic patients. Ventricular dysfunction without coronary atherosclerosis and hypertension is driven by hyperglycemia, hyperinsulinemia and impaired insulin signaling. Cardiomyocyte death, hypertrophy, fibrosis, and cell signaling defects underlie cardiom...