Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives

• Main Authors: Gantumur Battogtokh (Author), Yeon Su Choi (Author), Dong Seop Kang (Author), Sang Jun Park (Author), Min Suk Shim (Author), Kang Moo Huh (Author), Yong-Yeon Cho (Author), Joo Young Lee (Author), Hye Suk Lee (Author), Han Chang Kang (Author)
• Format: Book
• Published: Elsevier, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitochondrial targeting is a promising approach for solving current issues in clinical application of chemotherapy and diagnosis of several disorders. Here, we discuss direct conjugation of mitochondrial-targeting moieties to anticancer drugs, antioxidants and sensor molecules. Among them, the most...