Thiamylal serum concentration for refractory convulsive status epilepticus while associated decreased concentrations of concomitant antiepileptics: a case report

• Main Authors: Kazutaka Oda (Author), Tomomi Katanoda (Author), Hitomi Arakaki (Author), Taiki Katsume (Author), Kaho Matsuyama (Author), Hirofumi Jono (Author), Hideyuki Saito (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Treating refractory status epilepticus (RSE) remains a challenge. Thiamylal can be used as a second- or third-line treatment; however, its potential to induce cytochrome P450 (CYP) activity may reduce the concentration of antiepileptic drugs (AEDs) administered prior to thiamylal...