Combined MSC and GLP-1 Therapy Modulates Collagen Remodeling and Apoptosis following Myocardial Infarction

• Κύριοι συγγραφείς: Elizabeth J. Wright (Συγγραφέας), Nigel W. Hodson (Συγγραφέας), Michael J. Sherratt (Συγγραφέας), Moustapha Kassem (Συγγραφέας), Andrew L. Lewis (Συγγραφέας), Christine Wallrapp (Συγγραφέας), Nadim Malik (Συγγραφέας), Cathy M. Holt (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Hindawi Limited, 2016-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Background. Mesenchymal stem cells (MSCs) and glucagon-like peptide-1 (GLP-1) are being tested as treatment strategies for myocardial infarction (MI); however, their mechanisms in the heart are not fully understood. Methods. We examined the effects of MSCs, either native, or engineered to secrete a...