Comparison of three sample size calculation methods for non-inferiority vaccine trials with multiple continuous co-primary endpoints

Clinical trials that study immunogenicity of combination vaccines often have less power than desirable. To make up for the reduction in statistical power at the study level, researchers have to increase the study sample size. To study immunogenicity variables, we used the geometric mean concentratio...

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Main Authors: Jiaying Yang (Author), Jingxin Li (Author), Shiyuan Wang (Author), Li Luo (Author), Pei Liu (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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