Mid‐dosing interval concentration is important for polymyxin B exposure and acute kidney injury in critically ill patients

• Main Authors: Jing Wang (Author), Yuanchen Li (Author), Siqi Huang (Author), Min Wang (Author), Lu Jin (Author), Xuemei Luo (Author), Xiaoliang Cheng (Author), Na Yang (Author), Huaijun Zhu (Author)
• Format: Book
• Published: Wiley, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This study aimed to evaluate the association between polymyxin B (PMB) exposure and acute kidney injury (AKI) and analyze the risk factors for PMB‐induced AKI in critically ill patients. Plasma concentrations of PMB were determined using an ultraperformance liquid chromatography-tandem mass...