Tissue distribution of crizotinib and gemcitabine combination in a patient-derived orthotopic mouse model of pancreatic cancer

• Asıl Yazarlar: Richard J. Honeywell (Yazar), Amir Avan (Yazar), Elisa Giovannetti (Yazar), Godefridus J. Peters (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: International Association of Physical Chemists (IAPC), 2016-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Pharmacokinetics focuses on the question whether a drug actually reaches its target in therapeutic concentrations or accumulates elsewhere, potentially causing toxicological or unpredictable side effects. We determined tissue distribution of gemcitabine, an antimetabolite, and crizotinib, a tyrosine...