Trophoblast differentiation, invasion and hormone secretion in a three-dimensional in vitro implantation model with rhesus monkey embryos

• Main Authors: T. Arthur Chang (Author), Gennadiy I. Bondarenko (Author), Behzad Gerami-Naini (Author), Jessica G. Drenzek (Author), Maureen Durning (Author), Mark A. Garthwaite (Author), Jenna Kropp Schmidt (Author), Thaddeus G. Golos (Author)
• Format: Book
• Published: BMC, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The initiation of primate embryo invasion into the endometrium and the formation of the placenta from trophoblasts, fetal mesenchyme, and vascular components are essential for the establishment of a successful pregnancy. The mechanisms which direct morphogenesis of the chorionic...