Combined Treatment with Host-Directed and Anticytomegaloviral Kinase Inhibitors: Mechanisms, Synergisms and Drug Resistance Barriers

• Main Authors: Markus Wild (Author), Dubravka Karner (Author), Jan Eickhoff (Author), Sabrina Wagner (Author), Jintawee Kicuntod (Author), William Chang (Author), Peter Barry (Author), Stipan Jonjić (Author), Tihana Lenac Roviš (Author), Manfred Marschall (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite the availability of currently approved antiviral drugs, infections with human cytomegalovirus (HCMV) still cause clinically challenging, sometimes life-threatening situations. There is an urgent need for enhanced anti-HCMV drugs that offer improved efficacy, reduced dosages and options for l...