A Novel Strategy to Predict Carcinogenicity of Antiparasitics Based on a Combination of DNA Lesions and Bacterial Mutagenicity Tests

Genotoxicity and carcinogenicity testing of pharmaceuticals prior to commercialization is requested by regulatory agencies. The bacterial mutagenicity test was considered having the highest accuracy of carcinogenic prediction. However, some evidences suggest that it always results in false-positive...

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Main Authors: Qianying Liu (Author), Zhixin Lei (Author), Feng Zhu (Author), Awais Ihsan (Author), Xu Wang (Author), Zonghui Yuan (Author)
Format: Book
Published: Frontiers Media S.A., 2017-11-01T00:00:00Z.
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3rd Floor Main Library

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