The optimized drug delivery systems of treating cancer bone metastatic osteolysis with nanomaterials

• Main Authors: Xi Cheng (Author), Jinrong Wei (Author), Qi Ge (Author), Danlei Xing (Author), Xuefeng Zhou (Author), Yunzhu Qian (Author), Guoqin Jiang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Some cancers such as human breast cancer, prostate cancer, and lung cancer easily metastasize to bone, leading to osteolysis and bone destruction accompanied by a complicated microenvironment. Systemic administration of bisphosphonates (BP) or denosumab is the routine therapy for osteolysis but with...