Binary and Ternary Inclusion Complexes of Niflumic Acid: Synthesis, Characterization, and Dissolution Profile

• Main Authors: Zohra Bouchekhou (Author), Amel Hadj Ziane-Zafour (Author), Florentina Geanina Lupascu (Author), Bianca-Ștefania Profire (Author), Alina Nicolescu (Author), Denisse-Iulia Bostiog (Author), Florica Doroftei (Author), Ioan-Andrei Dascalu (Author), Cristian-Dragoș Varganici (Author), Mariana Pinteala (Author), Lenuta Profire (Author), Tudor Pinteala (Author), Bachir Bouzid (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although niflumic acid (NA) is one of the most used non-steroidal anti-inflammatory drugs, it suffers from poor solubility, low bioavailability, and significant adverse effects. To address these limitations, the complexation of NA with cyclodextrins (CDs) is a promising strategy. However, complexing...