Serofendic Acid Promotes Stellation Induced by cAMP and cGMP Analogs in Cultured Cortical Astrocytes

• Main Authors: Toshiaki Kume (Author), Ryo Ito (Author), Ryota Taguchi (Author), Yasuhiko Izumi (Author), Hiroshi Katsuki (Author), Tetsuhiro Niidome (Author), Yuki Takada-Takatori (Author), Hachiro Sugimoto (Author), Akinori Akaike (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated the effect of serofendic acid, a neuroprotective substance derived from fetal calf serum, on the morphological changes in cultured cortical astrocytes. Cultured astrocytes developed a stellate morphology with several processes following exposure to dibutylyl cAMP (dbcAMP), a membrane...