Polydeoxyribonucleotide, an Adenosine-A2A Receptor Agonist, Preserves Blood Testis Barrier from Cadmium-Induced Injury

• Main Authors: Francesco Squadrito (Author), Antonio Micali (Author), Mariagrazia Rinaldi (Author), Natasha Irrera (Author), Herbert Marini (Author), Domenico Puzzolo (Author), Antonina Pisani (Author), Cesare Lorenzini (Author), Andrea Valenti (Author), Rosaria Laurà (Author), Antonino Germanà (Author), Alessandra Bitto (Author), Gabriele Pizzino (Author), Giovanni Pallio (Author), Domenica Altavilla (Author), Letteria Minutoli (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cadmium (Cd) impairs blood-testis barrier (BTB). Polydeoxyribonucleotide (PDRN), an adenosine A2A agonist, has positive effects on male reproductive system. We investigated the effects of PDRN on the morphological and functional changes induced by Cd in mice testes. Adult Swiss mice were divided int...