Five Novel Polymorphs of Cardarine/GW501516 and Their Characterization by X-ray Diffraction, Computational Methods, Thermal Analysis and a Pharmaceutical Perspective

• Egile Nagusiak: Alexandru Turza (Egilea), Petru Pascuta (Egilea), Marieta Muresan-Pop (Egilea), Liviu Mare (Egilea), Gheorghe Borodi (Egilea), Violeta Popescu (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

GW501516, also known by the name of cardarine, is a synthetic peroxisome-proliferator-activated receptor delta (PPR-δ) agonist agent developed for applications in the treatment of metabolic disorders and cardiovascular diseases. A broad polymorph screening in various solvents and mixtures was comple...