Promotion of colorectal cancer cell death by ezetimibe via mTOR signaling-dependent mitochondrial dysfunction

• Main Authors: Yuanyuan Zheng (Author), Wenjuan Yang (Author), Yewei Jia (Author), Jie Ji (Author), Liwei Wu (Author), Jiao Feng (Author), Yan Li (Author), Ziqi Cheng (Author), Jie Zhang (Author), Jingjing Li (Author), Weiqi Dai (Author), Xuanfu Xu (Author), Jianye Wu (Author), Yingqun Zhou (Author), Chuanyong Guo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Colorectal cancer (CRC) is the fourth most common cancer worldwide, with high morbidity and mortality rates. In recent years, high-fat diet has been shown to increase CRC morbidity, highlighting the possibility of the application of hypolipidemic drugs for CRC treatment. In this study,...