Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue

• Main Authors: Radoslaw J. Gora (Author), Babette de Jong (Author), Patrick van Hage (Author), Mary Ann Rhiemus (Author), Fjodor van Steenis (Author), John van Noort (Author), Thomas Schmidt (Author), Marcel J. M. Schaaf (Author)
• Format: Book
• Published: The Company of Biologists, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Developments in single-molecule microscopy (SMM) have enabled imaging individual proteins in biological systems, focusing on the analysis of protein mobility patterns inside cultured cells. In the present study, SMM was applied in vivo, using the zebrafish embryo model. We studied dynamics of the me...