Molecular reductions in glucokinase activity increase counter-regulatory responses to hypoglycemia in mice and humans with diabetes
Objective: Appropriate glucose levels are essential for survival; thus, the detection and correction of low blood glucose is of paramount importance. Hypoglycemia prompts an integrated response involving reduction in insulin release and secretion of key counter-regulatory hormones glucagon and epine...
Saved in:
Main Authors: | Ali J. Chakera (Author), Paul S. Hurst (Author), Gill Spyer (Author), Emmanuel O. Ogunnowo-Bada (Author), William J. Marsh (Author), Christine H. Riches (Author), Chen-Yu Yueh (Author), S. Pauliina Markkula (Author), Jeffrey W. Dalley (Author), Roger D. Cox (Author), Ian A. Macdonald (Author), Stephanie A. Amiel (Author), Kenneth M. MacLeod (Author), Lora K. Heisler (Author), Andrew T. Hattersley (Author), Mark L. Evans (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2018-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Glucokinase mutation-a rare cause of recurrent hypoglycemia in adults: a case report and literature review
by: Oluremi N. Ajala, et al.
Published: (2016) -
Decreased expression of hepatic glucokinase in type 2 diabetes
by: Rebecca A. Haeusler, et al.
Published: (2015) -
A glucokinase-linked sensor in the taste system contributes to glucose appetite
by: Sandrine Chometton, et al.
Published: (2022) -
Impaired β-cell glucokinase as an underlying mechanism in diet-induced diabetes
by: Brian Lu, et al.
Published: (2018) -
Glucokinase as an emerging anti-diabetes target and recent progress in the development of its agonists
by: Yixin Ren, et al.
Published: (2022)