Optimal Treatment Selection in Sequential Systemic and Locoregional Therapy of Oropharyngeal Squamous Carcinomas: Deep Q-Learning With a Patient-Physician Digital Twin Dyad

• Principais autores: Elisa Tardini (Autor), Xinhua Zhang (Autor), Guadalupe Canahuate (Autor), Andrew Wentzel (Autor), Abdallah S R Mohamed (Autor), Lisanne Van Dijk (Autor), Clifton D Fuller (Autor), G Elisabeta Marai (Autor)
• Formato: Livro
• Publicado em: JMIR Publications, 2022-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

BackgroundCurrently, selection of patients for sequential versus concurrent chemotherapy and radiation regimens lacks evidentiary support and it is based on locally optimal decisions for each step. ObjectiveWe aim to optimize the multistep treatment of patients with head and neck cancer and predict...