Belzutifan, HIF-2α Inhibitor, and Clear Cell Renal Cell Carcinoma With Somatic Von-Hippel-Lindau Loss-of-Function Mutation

The Von-Hippel-Lindau (VHL) gene, acting as a tumor suppressor, plays a crucial role in the tumorigenesis of clear cell renal cell carcinoma (ccRCC). Approximately 90% of individuals with advanced ccRCC exhibit somatic mutations in the VHL gene. Belzutifan, orally administered small-molecule inhibit...

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Bibliographic Details
Main Authors: Kok Hoe Chan MD (Author), Ningjing Li MD (Author), Ran Lador MD (Author), Mark Amsbaugh MD (Author), Anneliese Gonzalez MD (Author), Putao Cen MD (Author)
Format: Book
Published: SAGE Publishing, 2024-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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