Assessing a Novel 3D Assay System for Drug Screening against OS Metastasis

• Main Authors: Natalie Koons (Author), Nicole Amato (Author), Scott Sauer (Author), David Warshawsky (Author), Dalit Barkan (Author), Chand Khanna (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteosarcoma (OS) is an aggressive mesenchymal cell tumor that carries a poor long-term prognosis. Despite definitive surgery for the primary tumor and adjuvant chemotherapy, pulmonary metastasis is common and is the primary cause of morbidity. To improve outcomes for patients, we have developed and...