m6A demethylase ALKBH5 drives denervation‐induced muscle atrophy by targeting HDAC4 to activate FoxO3 signalling

• Main Authors: Yuantong Liu (Author), Tianjian Zhou (Author), Qinghe Wang (Author), Runhan Fu (Author), Zengfu Zhang (Author), Nandi Chen (Author), Zhizhong Li (Author), Guoyong Gao (Author), Songlin Peng (Author), Dazhi Yang (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Skeletal muscle atrophy is a common clinical manifestation of various neurotrauma and neurological diseases. In addition to the treatment of primary neuropathies, it is a clinical condition that should be investigated. FoxO3 activation is an indispensable mechanism in denervation...