Establishment and Application of Engineered NIH 3T3 Cell Line with Stable Human RAGE Expression

• Main Authors: Xinyi Xiao (Author), Hui Chen (Author), Pameila Paerhati (Author), Meiqi Zhou (Author), Zhuoyi Yang (Author), Siyi Bai (Author), Yunsheng Yuan (Author)
• Format: Book
• Published: Georg Thieme Verlag KG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim NIH3T3 cell line with expression of human receptor for advanced glycation end-products (hRAGE) transduced with lentivirus vectors was used to analyze affinity, biological activity, and/or molecular mechanisms of molecules targeting the hRAGE pathway. Method The DNA fragment coding for hRAGE gene...