Inhibition of Leishmania Major PTR1 Gene Expression by Anti-sense in Escherichia Coli

Inhibition of Leishmania Major PTR1 Gene Expression by Anti-sense in Escherichia Coli

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Background:Protozoa related to Trypanosome family including Leishmania,synthesize enzymes to escape from drug therapy.One of them is PTR1 that its enzymatic activity is similar to dihydrofolate reductase(DHFR)Dihydrofolate reductase - thymidylate synthase has a major role in DNA synthesis, if it is...

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Bibliographic Details
Main Authors: M Mohebali (Author), F Mahboudi (Author), A Haghighi (Author), M Bandehpour (Author), F Kheirandish (Author), B Kazemi (Author)
Format: Book
Published: Tehran University of Medical Sciences, 2012-05-01T00:00:00Z.
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