The use of chitosan-coated flexible liposomes as a remarkable carrier to enhance the antitumor efficacy of 5-fluorouracil against colorectal cancer

• Main Authors: Abdullah Alomrani (Author), Mohamed Badran (Author), Gamaleldin I. Harisa (Author), Mohamed ALshehry (Author), Moayed Alhariri (Author), Aws Alshamsan (Author), Musaed Alkholief (Author)
• Format: Book
• Published: Elsevier, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Surface-coated nanocarriers have been extensively used to enhance the delivery of anticancer drugs and improve their therapeutic index. In this study, chitosan (CS)-coated flexible liposomes (chitosomes) containing 5-fluorouracil (5-FU) were designed and characterized for use as a novel approach to...