TLR4-TAK1-p38 MAPK pathway and HDAC6 regulate the expression of sigma-1 receptors in rat primary cultured microglia

Microglia maintain brain homeostasis as the main immune cells in the central nervous system. Activation of sigma-1 receptor (Sig1R) plays neuroprotective and anti-inflammatory roles in microglia. Recent studies showed that Sig1R expression level has been reduced in the brain of the patients with neu...

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Main Authors: Momoka Iwamoto (Author), Yoki Nakamura (Author), Masatoshi Takemura (Author), Kazue Hisaoka-Nakashima (Author), Norimitsu Morioka (Author)
Format: Book
Published: Elsevier, 2020-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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