Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages

• Main Authors: Hiroki Yamazaki (Author), Akifumi Kushiyama (Author), Hideyuki Sakoda (Author), Midori Fujishiro (Author), Takeshi Yamamotoya (Author), Yusuke Nakatsu (Author), Takako Kikuchi (Author), Sunao Kaneko (Author), Hirotoshi Tanaka (Author), Tomoichiro Asano (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sex hormone-binding globulin (SHBG) is a serum protein released mainly by the liver, and a low serum level correlates with a risk for metabolic syndrome including diabetes, obesity, and cardiovascular events. However, the underlying molecular mechanism(s) linking SHBG and metabolic syndrome remains...