Metabolic vulnerability of cancer stem cells and their niche

• Main Authors: Laura Marrone (Author), Simona Romano (Author), Chiara Malasomma (Author), Valeria Di Giacomo (Author), Andrea Cerullo (Author), Rosetta Abate (Author), Marialuisa Alessandra Vecchione (Author), Deborah Fratantonio (Author), Maria Fiammetta Romano (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer stem cells (CSC) are the leading cause of the failure of anti-tumor treatments. These aggressive cancer cells are preserved and sustained by adjacent cells forming a specialized microenvironment, termed niche, among which tumor-associated macrophages (TAMs) are critical players. The cycle of...