Quercetin Induces Apoptosis via Downregulation of Vascular Endothelial Growth Factor/Akt Signaling Pathway in Acute Myeloid Leukemia Cells

• Main Authors: Huan Shi (Author), Xin-Yu Li (Author), Yao Chen (Author), Xing Zhang (Author), Yong Wu (Author), Zi-Xuan Wang (Author), Pan-Hong Chen (Author), Hui-Qi Dai (Author), Ji Feng (Author), Sayantan Chatterjee (Author), Zhong-Jie Li (Author), Xiao-Wei Huang (Author), Hong-Qiao Wei (Author), Jigang Wang (Author), Guo-Dong Lu (Author), Jing Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute myeloid leukemia (AML) is an aggressive haematological malignancy characterized by highly proliferative accumulation of immature and dysfunctional myeloid cells. Quercetin (Qu), one kind of flavonoid, exhibits anti-cancer property in multiple types of solid tumor, but its effect on acute myelo...