Translating the Manufacture of Immunotherapeutic PLGA Nanoparticles from Lab to Industrial Scale: Process Transfer and In Vitro Testing

• Hoofdauteurs: Maria Camilla Operti (Auteur), Alexander Bernhardt (Auteur), Jeanette Pots (Auteur), Vladimir Sincari (Auteur), Eliezer Jager (Auteur), Silko Grimm (Auteur), Andrea Engel (Auteur), Anne Benedikt (Auteur), Martin Hrubý (Auteur), Ingrid Jolanda M. De Vries (Auteur), Carl G. Figdor (Auteur), Oya Tagit (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Poly(lactic-co-glycolic acid) (PLGA) nanoparticle-based drug delivery systems are known to offer a plethora of potential therapeutic benefits. However, challenges related to large-scale manufacturing, such as the difficulty of reproducing complex formulations and high manufacturing costs, hinder the...