Wild-type Drosophila melanogaster as an alternative model system for investigating the pathogenicity of Candida albicans

• Autors principals: Marcus T. Glittenberg (Autor), Sukrit Silas (Autor), Donna M. MacCallum (Autor), Neil A. R. Gow (Autor), Petros Ligoxygakis (Autor)
• Format: Llibre
• Publicat: The Company of Biologists, 2011-07-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

SUMMARY Candida spp. are opportunistic pathogens in humans, and their systemic infections display upwards of 30% mortality in immunocompromised patients. Current mammalian model systems have certain disadvantages in that obtaining results is time consuming owing to the relatively long life spans and...