The Interaction of Fluorinated Glycomimetics with DC-SIGN: Multiple Binding Modes Disentangled by the Combination of NMR Methods and MD Simulations

The Interaction of Fluorinated Glycomimetics with DC-SIGN: Multiple Binding Modes Disentangled by the Combination of NMR Methods and MD Simulations

Fluorinated glycomimetics are frequently employed to study and eventually modulate protein-glycan interactions. However, complex glycans and their glycomimetics may display multiple binding epitopes that enormously complicate the access to a complete picture of the protein-ligand complexes. We herei...

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Main Authors: J. Daniel Martínez (Author), Angela S. Infantino (Author), Pablo Valverde (Author), Tammo Diercks (Author), Sandra Delgado (Author), Niels-Christian Reichardt (Author), Ana Ardá (Author), Francisco Javier Cañada (Author), Stefan Oscarson (Author), Jesús Jiménez-Barbero (Author)
Format: Book
Published: MDPI AG, 2020-08-01T00:00:00Z.
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3rd Floor Main Library

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