Rosiglitazone Protects Endothelial Cells From Irradiation-Induced Mitochondrial Dysfunction

• Main Authors: Bjorn Baselet (Author), Ronald B. Driesen (Author), Emma Coninx (Author), Niels Belmans (Author), Tom Sieprath (Author), Ivo Lambrichts (Author), Winnok H. De Vos (Author), Sarah Baatout (Author), Pierre Sonveaux (Author), An Aerts (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and PurposeUp to 50-60% of all cancer patients receive radiotherapy as part of their treatment strategy. However, the mechanisms accounting for increased vascular risks after irradiation are not completely understood. Mitochondrial dysfunction has been identified as a potential cause of r...