Evaluating immune response in vitro in a relevant microenvironment: a high-throughput microfluidic model for clinical screening

• Main Authors: Flora Doffe (Author), Layla Fuoco (Author), Judith Michels (Author), Sandra Jernström (Author), Raphael Tomasi (Author), Pierre Savagner (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Functional screening of new pharmaceutical compounds requires clinically relevant models to monitor essential cellular and immune responses during cancer progression, with or without treatment. Beyond survival, the emergence of resistant tumor cell clones should also be considered, including sp...