Metabolism-Based Therapeutic Strategies Targeting Cancer Stem Cells

• 主要な著者: Petra Jagust (著者), Beatriz de Luxán-Delgado (著者), Beatriz Parejo-Alonso (著者), Patricia Sancho (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Cancer heterogeneity constitutes the major source of disease progression and therapy failure. Tumors comprise functionally diverse subpopulations, with cancer stem cells (CSCs) as the source of this heterogeneity. Since these cells bear in vivo tumorigenicity and metastatic potential, survive chemot...