Miniaturization and Automation of a Human In Vitro Blood-Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery

• Main Authors: Elisa L. J. Moya (Author), Elodie Vandenhaute (Author), Eleonora Rizzi (Author), Marie-Christine Boucau (Author), Johan Hachani (Author), Nathalie Maubon (Author), Fabien Gosselet (Author), Marie-Pierre Dehouck (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Central nervous system (CNS) diseases are one of the top causes of death worldwide. As there is a difficulty of drug penetration into the brain due to the blood-brain barrier (BBB), many CNS drugs treatments fail in clinical trials. Hence, there is a need to develop effective CNS drugs following str...